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“A localized protective response elicited by injury or destruction of tissues, which serves to destroy, dilute, or wall off both the injurious agent and the injured tissue.”
“It is defined as the process of reaction of living tissues to injury or irritation involving a series of vascular, cellular and chemical mediator events.”
Inflammation is a tissue reaction that rapidly delivers mediators of host defense , circulating cells and proteins to the locations where they are needed i.e at the sites of infection and tissue damage.
The aims and purposes of the inflammatory reaction are :
Causes of inflammation
Living agents like micro-organisms, including bacteria, viruses, parasites, fungi.Non living agents including toxins, sera, animal stings, snake poisons.
2. Chemical agents
Any chemical may result in tissue damage and inflammation.
3. Physical agents
Fractures, soft tissue injuries, radiation damage, exposure to extremes of temperature like burns radiation, and frostbite can damage tissues.
3. Inert bodies
Inert bodies like thorns, glass, stone, nails etc. can cause inflammation.
4. Another cause can be development of necrosis like infarct, thrombus or atheroma in an artery or tumor inside the body.
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